Molecular Mechanisms of Resistance to Hormonal Therapy of Prostate Cancer (122)
Posted by: University of Texas Southwestern Medical Center
Posted date: 19-Jan-10
Molecular Mechanisms of Resistance to Hormonal Therapy of Prostate Cancer (122)
A postdoctoral position is available in the laboratory of Dr. Nima Sharifi in the Division of Hematology/Oncology. This laboratory is focused on molecular mechanisms of androgen receptor (AR) gain-of-function that lead to resistance to androgen deprivation therapy and the translational relevance thereof. Areas of interest in this laboratory include: 1) Specific mechanisms that lead to ligand-independent AR gain-of-function. 2) Metabolic and genetic changes required for androgen synthesis from adrenal precursors. 3) Animal models of advanced prostate cancer that are useful for translational and therapeutic studies. The candidate should hold a doctoral degree with a background in transcriptional regulation, metabolism or cancer biology. Candidates with an interest in the position should send their CV and contact information for 3 references to: Nima Sharifi, M.D. Assistant Professor Division of Hematology/Oncology UT Southwestern Medical Center 5323 Harry Hines Blvd. Dallas, TX 75390-8852 c/o Hem/Onc Research HemOncResearch utsouthwestern.edu UT Southwestern Medical Center at Dallas is an Equal Opportunity, Affirmative Action Employer.  
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